Stem cell therapy utilizing umbilical derived mesenchymal stem cells (MSCs) continues to show tremendous success in the treatment of Parkinson’s Disease (PD) and various other neurodegenerative disorders. MSCs are unique in their ability to differentiate into different cell types, including neurons and glia, as well as to secrete growth factors and other signaling molecules that can help to promote nerve cell survival and repair.
One of the major advantages of umbilical derived mesenchymal stem cells (MSCs) is their ability to migrate to sites of injury or disease in the brain. This makes them an attractive option for the treatment of Parkinson’s Disease, where degeneration of dopamine-producing neurons in the substantia nigra is the primary cause of motor symptoms such as tremors, rigidity, and bradykinesia. Mesenchymal stem cells have been shown to migrate to the damaged areas of the brain and to secrete growth factors that can help to protect and repair dopamine-producing neurons.
Can mesenchymal stem cells aid dopamine production?
Another benefit of Mesenchymal stem cells is their ability to modulate the immune system.
In Parkinson’s Disease, the immune system can contribute to the degeneration of dopamine-producing neurons through the production of pro-inflammatory cytokines and the activation of immune cells.
Mesenchymal stem cells have been shown to suppress the activation of immune cells and to reduce the production of pro-inflammatory cytokines, and this is how they help to protect dopamine-producing neurons from immune-mediated damage.
In addition to their neuroprotective and immunomodulatory effects, Mesenchymal stem cells directly differentiate into dopamine-producing neurons. These newly developed neurons integrate into the existing dopamine neuronal network.
Thus, creating new dopamine-producing cells in the brain. MSCs restore the functional capacity of the dopamine neuronal system, which helps to alleviate the motor symptoms of Parkinson’s Disease.
Is stem cell therapy safe for the treatment of Parkinson’s Disease?
The safety of Mesenchymal stem cells has also been demonstrated in clinical trials for PD as well as other neurological conditions, such as spinal cord injury and stroke. These trials have shown that MSCs are well tolerated. This suggests that stem cell therapy utilizing umbilical derived mesenchymal stem cells are a safe and effective treatment option for Parkinson’s Disease.
Stem cell therapy utilizing MSCs offers a promising cutting edge approach to the treatment of Parkinson’s disease.
Their ability to migrate to sites of injury or disease, modulate the immune system, differentiate into dopamine-producing neurons, and their demonstrated safety in clinical trials make them an attractive option for the treatment of Parkinson’s Disease.
What does it cost the average patient to live with Parkinson’s Disease?
According to The National Institutes of Health the annual cost of living with Parkinson’s Disease has risen from significantly over the last 20 years. In 2002 the average costs ranged from $1750 to $17,560.
In 2010 it was closer to $23,000 and it is now estimated at $63,569. Insurance covers some of the expense but the patient will experience significant out-of-pocket costs, NIH estimates that 28% of the total cost is borne by the patient or family.
Non-medical costs are estimated to total between $8,000 and $10,000 annually for a person with PD. These expenses are not covered by insurance.
The cost of stem cell therapy for Parkinson’s Disease.
Quality of life with Parkinson’s Disease – Can it be restored?
Parkinson’s disease affects an individual’s quality of life in several ways:
- Mobility issues: People with Parkinson’s may experience tremors, stiffness, and difficulty with balance, which can make it difficult to perform daily activities and maintain independence.
- Fatigue: People with Parkinson’s may experience tiredness and a decrease in energy levels, which can limit their ability to engage in physical and mental activities.
- Cognitive changes: Some individuals with Parkinson’s may experience changes in thinking, memory, and attention, which can affect their ability to perform tasks and communicate effectively.
- Emotional changes: Parkinson’s can also have an impact on a person’s emotional well-being, causing depression, anxiety, and stress.
- Sleep problems: Parkinson’s can cause sleep disturbances, including insomnia and vivid dreaming, which can further impact a person’s overall quality of life.
For the reasons listed earlier in this article, mesenchymal stem cells have helped many people with Parkinson’s Disease experience a much better quality of life.
Why should you consider stem cell treatment for Parkinson’s Disease?
The life expectancy of a person with Parkinson’s disease varies and can depend on a number of factors such as the age of onset, the rate of progression of the disease, overall health and medical management. On average, however, people with Parkinson’s disease tend to live about 5-10 years less than the general population.
It’s important to note that Parkinson’s disease is a chronic condition and not a terminal illness, and many people with Parkinson’s can live a full and active life for many years after diagnosis. With appropriate medical care, and support from loved ones, individuals with Parkinson’s can lead fulfilling lives.
Stem cell therapy helps to replace damaged cells, reduce inflammation, and improve the function of neurons that are responsible for producing dopamine, a neurotransmitter that is important for controlling movement. It can improve your quality of life and potentially extend your life. There are virtually no side-effects and stem cell therapy has been deemed safe in clinical trials.